Essence Harden is the co-curator of Made in LA, 2025, at The Hammer Museum and Curator of the Focus section for Frieze LA, 2024 and 2025. Essence has curated exhibitions at the California African American Museum (CAAM), The Orange County Museum of Art (OCMA), Art + Practice, Los Angeles Contemporary Exhibitions (LACE), Museum of the African Diaspora (MoAD), and Oakland Museum of California, amongst others.

Essence is a contributor to The Los Angeles Times Magazine: Image, SSENSE, Art21, Contemporary Art Review LA (CARLA), Artsy, Cultured Magazine, Performa Magazine, and S has written catalog entries for California Biennial: Pacific Gold; Made in LA: Acts of Living; Prospect 5: Yesterday we said tomorrow;  Brave New Worlds: Exploration of Space: Palm Springs Art Museum; and What Needs to Be Said: Hallie Ford Fellows Exhibition. Essence has also served as an art consultant for film and television.

Essence is a 2018 recipient of The Creative Capital, Andy Warhol Foundation Arts Writers Grant, and a 2020 Annenberg Innovation Lab Civic Media Fellow.

Essence previously served as a Visual Arts Curator at the California African American Museum.